Anti-Epileptic Medication Exposure Influences Functional Status in New Zealand Stroke Patients: A Retrospective Population-Level Study.

ABSTRACT:

Background

Patients who develop seizures after stroke have disproportionately poorer outcomes and increased mortality.

Objective

Our objective was to investigate whether exposure to anti-epileptic medications influenced long-term functional status after stroke.

Methods

We used linked health administrative data from a cohort of adult stroke patients in New Zealand. Demographics and prescription information were obtained from the National Minimum Dataset and Pharmaceutical Collection, respectively. Activities of daily living (ADL) scores for the same patients were obtained using the International Resident Assessment Instrument. Beta regression was used to investigate the relationship between anti-epileptic drug (AED) exposure and functional status.

Results

The st

SUBMITTER: McGregor AL 

PROVIDER: S-EPMC8844337 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature