Use of Drugs with Anticholinergic Properties at Hospital Admission Associated with Mortality in Older Patients: A Danish Nationwide Register-Based Cohort Study.

ABSTRACT:

Background

Use of drugs with anticholinergic properties (DAP) has a negative impact on older people.

Objective

Our aim was to examine the association between DAP at hospital admission and mortality in older patients.

Patients and methods

We performed a nationwide population-based cohort study including patients aged ≥ 65 years admitted to Danish geriatric medicine departments during 2005-2014. National health registers were used to link with individual-level data. Patients were followed to emigration, death, or study termination (31 December 2015). DAP was defined as medications included in the anticholinergic cognitive burden (ACB) scale, which assigns each DAP a score between 1 and 3. The individual ACB score was calculated and the number of DAP counted. We used Cox

SUBMITTER: Sorensen SR 

PROVIDER: S-EPMC8844340 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature