Vulvar Paget's disease associated with squamous cell carcinoma: A case report.

ABSTRACT:

Introduction

and Importance: Extra Mammary Paget's disease (EMPD) of the vulva, a rare postmenopausal entity, is responsible for less than 1% of all vulvar neoplasms. Invasive EMPD of the vulva with underlying squamous cell carcinoma is even rare.

Case presentation

A 70-year-old para 5 postmenopausal lady presented with a history of vulvar itching and a gradually progressive reddish lesion on genitals unresolved by topical therapies for one year. Vulvar biopsy confirmed the presence of pagetoid cells with a focus of squamous invasion.

Discussion

The clinical presentation is often non-specific and typically presents as a pruritic skin rash in the vulva. Optimal management of EMPD of the vulva is unclear, but wide surgical excision is considered the standard therapeutic

SUBMITTER: Bajracharya A 

PROVIDER: S-EPMC8844793 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature