Automated data analytics workflow for stability experiments based on regression analysis.

ABSTRACT:

Introduction

We define a designated data analytics workflow for the evaluation of stability experiments, which takes all data situations into account. This complements the evaluation described by the CLSI EP25 [1] guideline by including a targeted exception handling algorithm and thus allows one to automatically evaluate stability data based on linear regression analysis.

Description

The evaluation of stability experiments based on regression analysis requires the calculation of the confidence interval of the regression line. The stability time is estimated at the intersection of the confidence interval with the acceptance criterion. This approach results in solving a quadratic equation, with factors that depend on the estimated intercept, slope, the measurement variability

SUBMITTER: Geistanger A 

PROVIDER: S-EPMC8844906 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature