Synergic fabrication of multifunctional liposomes nanocomposites for improved radiofrequency ablation combination for liver metastasis cancer therapy.

ABSTRACT: The field of biomedical research has recently been interested in nanoplatforms with various functionalities, such as cancer drug carriers and MRI and optical imaging, as well as thermal treatment, among other things. As a result of the present investigation, a unique multifunctional liposome (MFL) was established in this investigation. Using radiofrequency-induced imaging and drug release based on magnetic field impact, a dual drug delivery targeted with tumor multi-mechanism treatment was made more effective. The C60 (fullerene) surface was coated with iron nanocomposites to establish the proposed nanosystems, and PEGylation was used (Fe₃O₄-C60-PEG₂₀₀₀). For fullerene radiofrequency-triggered drug release, thermosensitive DPPC liposomes with folate-DSPE-PE

SUBMITTER: Zhang N 

PROVIDER: S-EPMC8845112 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature