Antimicrobial-associated organ injury among the elderly: a systematic review and meta-analysis protocol.

ABSTRACT:

Introduction

Older adults (aged 65 years and above) constitute the fastest growing population cohort in the western world. There is increasing evidence that the burden of infections disproportionately affects this cohort of older adults and hence this vulnerable population is frequently exposed to antimicrobials. There is currently no systematic review summarising the evidence for risk of organ injury following antimicrobial exposure among older adults. This protocol will outline how we will conduct a systematic review and meta-analyses to examine the relationship between antimicrobial exposure and organ injury in older adults.

Methods and analysis

We will search for PsycINFO, PubMed and EMBASE databases for relevant articles using MeSH terms where applicable. After removing

SUBMITTER: Chinzowu T 

PROVIDER: S-EPMC8845168 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature