Serendipity Reveals the Function and Physiological Role of a Large Family of Proteins.
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ABSTRACT:
SUBMITTER: Downs D
PROVIDER: S-EPMC8846392 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Publications
Serendipity Reveals the Function and Physiological Role of a Large Family of Proteins.
Journal of bacteriology 20211206 2
Microbial metabolism involves a complex set of interactions between metabolic pathways that include proteins of both known and uncharacterized function. While investigating the physiological strategy used by actinomycetes with two RpoB paralogs, Damiano et al. uncovered the endonuclease activity of a member of the Rid family (F. Damiano, M. Calcagnile, D. Pasanisi, A. Talà, et al., J Bacteriol, 204:e00462-21, 2022, https://doi.org/10.1128/JB.00462-21). While this finding was peripheral to the or ...[more]
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