Helicobacter typhlonius sp. nov., a Novel Murine Urease-Negative Helicobacter Species.

ABSTRACT: Over the past decade, several Helicobacter species have been isolated from rodents. With the advent of PCR for the diagnosis of infectious agents, it has become clear that several previously uncharacterized Helicobacter species also colonize rodents. In this report, we describe a novel urease-negative helicobacter, Helicobacter typhlonius sp. nov., which was isolated from colonies of laboratory mice independently by two laboratories. Infection of immunodeficient mice by this bacterium resulted in typhlocolitis similar to that observed with other helicobacter infections. H. typhlonius is genetically most closely related to H. hepaticus. Like H. hepaticus, it is a spiral bacterium with bipolar sheathed flagella. However, this novel species contains a large intervening sequence in its 16S rRN

SUBMITTER: Franklin CL 

PROVIDER: S-EPMC88465 | biostudies-literature | 2001 Nov

REPOSITORIES: biostudies-literature