Chromosome-level genome of Schistosoma haematobium underpins genome-wide explorations of molecular variation.

ABSTRACT: Urogenital schistosomiasis is caused by the blood fluke Schistosoma haematobium and is one of the most neglected tropical diseases worldwide, afflicting > 100 million people. It is characterised by granulomata, fibrosis and calcification in urogenital tissues, and can lead to increased susceptibility to HIV/AIDS and squamous cell carcinoma of the bladder. To complement available treatment programs and break the transmission of disease, sound knowledge and understanding of the biology and ecology of S. haematobium is required. Hybridisation/introgression events and molecular variation among members of the S. haematobium-group might effect important biological and/or disease traits as well as the morbidity of disease and the effectiveness of control programs including mass drug administratio

SUBMITTER: Stroehlein AJ 

PROVIDER: S-EPMC8846543 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature