Neonatal amygdala resting-state functional connectivity and socio-emotional development in very preterm children.

ABSTRACT: Very preterm children are more likely to exhibit difficulties in socio-emotional processing than their term-born peers. Emerging socio-emotional problems may be partly due to alterations in limbic system development associated with infants' early transition to extrauterine life. The amygdala is a key structure in this system and plays a critical role in various aspects of socio-emotional development, including emotion regulation. The current study tested the hypothesis that amygdala resting-state functional connectivity at term-equivalent age would be associated with socio-emotional outcomes in childhood. Participants were 129 very preterm infants (<33 weeks' gestation) who underwent resting-state functional MRI at term and received a neurodevelopmental assessment at 4-7 years (median = 4.

SUBMITTER: Kanel D 

PROVIDER: S-EPMC8846580 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature