Metabolic associated fatty liver disease is a risk factor for chronic kidney disease.

ABSTRACT:

Background and aims

To clarify the relationship between metabolic dysfunction-associated fatty liver disease (MAFLD) and chronic kidney disease (CKD).

Methods

The participants were divided into four groups by the presence or absence of fatty liver disease (FLD) and metabolic dysfunction (MD). MAFLD was defined as having both FLD and MD, whereas CKD was defined as having an estimated glomerular filtration rate of <60 mL/min/1.73 m² and/or proteinuria.

Results

In this cross-sectional study of 27,371 participants, the proportions of those in the non-FLD without MD, non-FLD with MD, FLD without MD, and MAFLD groups were 48.7, 28.2, 2.3, and 20.8%, respectively. Compared with non-FLD without MD, MAFLD was associated with the risk of CKD (adjusted odds ratio 1.83

SUBMITTER: Hashimoto Y 

PROVIDER: S-EPMC8847128 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature