Weight changes, metabolic syndrome and all-cause mortality among Asian adults living with HIV.

ABSTRACT:

Objectives

We investigated weight changes following antiretroviral therapy (ART) initiation, the development of metabolic syndrome (MetS) and its association with all-cause mortality among Asian adults living with HIV.

Methods

Participants enrolled in a regional Asian HIV-infected cohort with weight and height measurements at ART initiation were eligible for inclusion in the analysis. Factors associated with weight changes and incident MetS (according to the International Diabetic Federation (IDF) definition) were analysed using linear mixed models and Cox regression, respectively. Competing-risk regression models were used to investigate the association of MetS with all-cause mortality.

Results

Among 4931 people living with HIV (PLWH), 66% were male. At ART initiatio

SUBMITTER: Han WM 

PROVIDER: S-EPMC8847330 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature