Finite element modeling of the complex anisotropic mechanical behavior of the human sclera and pia mater.

ABSTRACT:

Background and objective

Accurate finite element (FE) simulation of the optic nerve head (ONH) depends on accurate mechanical properties of the load-bearing tissues. The peripapillary sclera in the ONH exhibits a depth-dependent, anisotropic, heterogeneous collagen fiber distribution. This study proposes a novel cable-in-solid modeling approach that mimics heterogeneous anisotropic collagen fiber distribution, validates the approach against published experimental biaxial tensile tests of scleral patches, and demonstrates its effectiveness in a complex model of the posterior human eye and ONH.

Methods

A computational pipeline was developed that defines control points in the sclera and pia mater, distributes the depth-dependent circumferential, radial, and isotropic cable elem

SUBMITTER: Karimi A 

PROVIDER: S-EPMC8847341 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature