Transcriptome analysis reveals the potential roles of long non-coding RNAs in feed efficiency of chicken.

ABSTRACT: Feed efficiency is an important economic trait and reduces the production costs per unit of animal product. Up to now, few studies have conducted transcriptome profiling of liver tissue in feed efficiency-divergent chickens (Ross vs native breeds). Also, molecular mechanisms contributing to differences in feed efficiency are not fully understood, especially in terms of long non-coding RNAs (lncRNAs). Hence, transcriptome profiles of liver tissue in commercial and native chicken breeds were analyzed. RNA-Seq data along with bioinformatics approaches were applied and a series of lncRNAs and target genes were identified. Furthermore, protein-protein interaction network construction, co-expression analysis, co-localization analysis of QTLs and functional enrichment analysis were used to functi

SUBMITTER: Karimi P 

PROVIDER: S-EPMC8847365 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature