Outcome Measures for Dementia With Lewy Body Clinical Trials: A Review.

ABSTRACT:

Background

Dementia with Lewy bodies (DLB) is one of the most common degenerative dementias. Clinical trials for individuals with DLB are increasing. We aimed to identify commonly used outcome measures for trials in DLB.

Methods

A pragmatic literature search of PubMed and clinicaltrials.gov identified interventional studies including populations with DLB. Studies were included if they enrolled participants with DLB and met the National Institutes of Health criteria for a clinical trial. Data were collected using standardized forms. Outcome measures were categorized according to core and supportive features of DLB.

Results

After de-duplication, 58 trials were identified. The most common cognitive outcome measures were the Mini Mental State Examination (n=24) and Cognit

SUBMITTER: Patel B 

PROVIDER: S-EPMC8847491 | biostudies-literature | 2022 Jan-Mar 01

REPOSITORIES: biostudies-literature