Neuronal modulation in the mouse superior colliculus during covert visual selective attention.

ABSTRACT: Covert visual attention is accomplished by a cascade of mechanisms distributed across multiple brain regions. Visual cortex is associated with enhanced representations of relevant stimulus features, whereas the contributions of subcortical circuits are less well understood but have been associated with selection of relevant spatial locations and suppression of distracting stimuli. As a step toward understanding these subcortical circuits, here we identified how neuronal activity in the intermediate layers of the superior colliculus (SC) of head-fixed mice is modulated during covert visual attention. We found that spatial cues modulated both firing rate and spike-count correlations. Crucially, the cue-related modulation in firing rate was due to enhancement of activity at the cued spatial l

SUBMITTER: Wang L 

PROVIDER: S-EPMC8847498 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature