Effectiveness of a 6-Month Isoniazid on Prevention of Incident Tuberculosis Among People Living with HIV in Eritrea: A Retrospective Cohort Study.

ABSTRACT:

Introduction

A 6-month isoniazid as tuberculosis preventive therapy (TPT) for people living with HIV (PLHIV) was nationally introduced in Eritrea in 2014. However, its effectiveness in preventing tuberculosis (TB) and duration of protection was questioned by physicians. This study was, therefore, conducted to evaluate the impact of the isoniazid preventive therapy (IPT) primarily on the prevention of TB and duration of its protection in PLHIV.

Methods

A retrospective cohort study was conducted that selected all eligible PLHIV attending HIV care clinics in all national and regional referral hospitals in Eritrea. Data was collected from patients' clinical cards using a structured data extraction sheet. The association between use of IPT and outcomes of interest was assessed us

SUBMITTER: Russom M 

PROVIDER: S-EPMC8847634 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature