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Data of Nebivolol on oxidative stress parameters in hypertensive patients.


ABSTRACT: Oxidative stress is a key feature in hypertension, since reactive oxygen species are involved in all stages of cardiovascular diseases. Saliva is a body fluid that can be used to investigate alterations in the oxidative system with several specific advantages over blood. Nebivolol is a third-generation selective β1-adrenergic receptor antagonist that promotes vasodilation and has been shown to reduce oxidative stress in pre-clinical and clinical studies. The use of Nebivolol in different periods of treatment demonstrated that it is an efficient anti-hypertensive drug. We evaluated the oxidative stress biomarkers and the enzymatic and non-enzymatic antioxidant systems in saliva of hypertensive patients before and after the use of anti-hypertensive therapeutic doses of Nebivolol, since saliva can be used as an auxiliary tool to analyze parameters of oxidative stress.

SUBMITTER: Barroso HC 

PROVIDER: S-EPMC8847804 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature

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Data of Nebivolol on oxidative stress parameters in hypertensive patients.

Barroso Helena C HC   Graton Murilo E ME   Potje Simone R SR   Troiano Jéssica A JA   Silva Lilian X LX   Nakamune Ana Cláudia M S ACMS   Antoniali Cristina C  

Data in brief 20220203


Oxidative stress is a key feature in hypertension, since reactive oxygen species are involved in all stages of cardiovascular diseases. Saliva is a body fluid that can be used to investigate alterations in the oxidative system with several specific advantages over blood. Nebivolol is a third-generation selective β1-adrenergic receptor antagonist that promotes vasodilation and has been shown to reduce oxidative stress in pre-clinical and clinical studies. The use of Nebivolol in different periods  ...[more]

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