Stereotactic radiotherapy for soft tissue and bone sarcomas: real-world evidence.

ABSTRACT:

Introduction

Selected patients with locally advanced or metastatic soft tissue and bone sarcomas (STBS) may benefit from intensive local treatment, such as stereotactic radiotherapy (SRT). This study aimed to summarize the utilization and outcomes of SRT in STBS and to identify predictive factors for progression and survival.

Materials and methods

Consecutive patients with advanced STBS who underwent STBS in a sarcoma tertiary center were identified. We collected tumor- and treatment-related factors. Endpoints comprised time to local progression (TTLP), local progression-free survival (LPFS), time to progression, progression-free survival, and overall survival (OS). The Cox proportional-hazards model was used to identify prognostic factors.

Results

We identified 141 p

SUBMITTER: Spalek MJ 

PROVIDER: S-EPMC8848098 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature