An Epigenetic Perspective on Lifestyle Medicine for Depression: Implications for Primary Care Practice.

ABSTRACT: Depression is the most common presenting mental health disorder in primary care. It is also a major contributor to somatic complaints, worsening of chronic medical conditions, poor quality of life, and suicide. Current pharmacologic and psychotherapeutic approaches avert less than half of depression's cumulative burden on society. However, there is a growing body of research describing both how maladaptive lifestyle choices contribute to the development and worsening of depression and how lifestyle-oriented medical interventions can reduce the incidence and severity of depression. This research, largely derived from an emerging field called epigenetics, elucidates the interactions between our lifestyle choices and those epigenetic factors which mediate our tendencies toward either health,

SUBMITTER: Lee JS 

PROVIDER: S-EPMC8848122 | biostudies-literature | 2022 Jan-Feb

REPOSITORIES: biostudies-literature