Patients' Perspectives on Transforming Clinical Trial Participation: Large Online Vignette-based Survey.

ABSTRACT:

Background

Patients' participation is crucial to the success of randomized controlled trials (RCTs). However, recruiting and retaining patients in trials remain a challenge.

Objective

This study aims to describe patients' preferences for the organization of RCTs (visits on- site or remotely) and evaluate the potential impact of fulfilling preferences on their willingness to participate in a clinical trial.

Methods

This was a vignette-based survey. Vignettes were case scenarios of real clinical trials assessing pharmacological treatments. These RCTs evaluated 6 prevalent chronic diseases (ie, osteoporosis, osteoarthritis, asthma, cardiovascular diseases, diabetes, and endometriosis). Each vignette described (1) the RCT and characteristics of the treatment tested (ie, d

SUBMITTER: Nguyen VT 

PROVIDER: S-EPMC8848233 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature