Fully resolved assembly of Cryptosporidium parvum.

ABSTRACT:

Background

Cryptosporidium parvum is an apicomplexan parasite commonly found across many host species with a global infection prevalence in human populations of 7.6%. Understanding its diversity and genomic makeup can help in fighting established infections and prohibiting further transmission. The basis of every genomic study is a high-quality reference genome that has continuity and completeness, thus enabling comprehensive comparative studies.

Findings

Here, we provide a highly accurate and complete reference genome of Cryptosporidium parvum. The assembly is based on Oxford Nanopore reads and was improved using Illumina reads for error correction. We also outline how to evaluate and choose from different assembly methods based on 2 main approaches that can be applied to o

SUBMITTER: Menon VK 

PROVIDER: S-EPMC8848321 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature