Bone marrow-derived mononuclear stem cells in the treatment of retinal degenerations.

ABSTRACT: Retinal degenerative diseases affecting the outer retina in its many forms (inherited, acquired or induced) are characterized by photoreceptor loss, and represent currently a leading cause of irreversible vision loss in the world. At present, there are very few treatments capable of preventing, recovering or reversing photoreceptor degeneration or the secondary retinal remodeling, which follows photoreceptor loss and can also cause the death of other retinal cells. Thus, these diseases are nowadays one of the greatest challenges in the field of ophthalmological research. Bone marrow derived-mononuclear stem cell transplantation has shown promising results for the treatment of photoreceptor degenerations. These cells may have the potential to slow down photoreceptor loss, and therefore shou

SUBMITTER: Garcia-Ayuso D 

PROVIDER: S-EPMC8848608 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature