The accuracy of D-dimer in the diagnosis of periprosthetic infections: a systematic review and meta-analysis.

ABSTRACT:

Background

Periprosthetic joint infection (PJI) is a devastating complication after total hip arthroplasty (THA) or total knee arthroplasty (TKA). It is scarce and contradicting evidence supporting the use of serum D-dimer to diagnose PJI in revision THA and TKA. This systematic review and meta-analysis aimed to investigate the accuracy of D-dimer in the diagnosis of periprosthetic infections.

Methods

The PubMed, Embase, Web of Science were systematically searched from the inception dates to August 15, 2020. We included all diagnostic studies of D-dimer in the diagnosis of periprosthetic infections. The literature's quality was evaluated by the QUADAS-2 tool, and Stata16 and Revman5.3 software carried out the meta-analysis.

Results

Of 115 citations identified by the s

SUBMITTER: Wang R 

PROVIDER: S-EPMC8848660 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature