Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus.

ABSTRACT:

Background

Cashmere goat is famous for its high-quality fibers. The growth of cashmere in secondary hair follicles exhibits a seasonal pattern arising from circannual changes in the natural photoperiod. Although several studies have compared and analyzed the differences in gene expression between different hair follicle growth stages, the selection of samples in these studies relies on research experience or morphological evidence. Distinguishing hair follicle growth cycle according to gene expression patterns may help to explore the regulation mechanisms related to cashmere growth and the effect of melatonin from a molecular level more accurately.

Results

In this study, we applied RNA-sequencing to the hair follicles of three normal and three melatonin-treated Inner Mongoli

SUBMITTER: Li C 

PROVIDER: S-EPMC8848980 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature