Temperature-Dependent Reversible Morphological Transformations in N-Oleoyl β-d-Galactopyranosylamine.

ABSTRACT: Amphiphilic molecules self-assemble into supramolecular structures of various sizes and morphologies depending on their molecular packing and external factors. Transformations between various self-assembled morphologies are a matter of great fundamental interest. Recently, we reported the discovery of a novel class of single-chain galactopyranosylamide amphiphiles that self-assemble to form vesicles in water. Here, we describe how the vesicles composed of the amphiphile N-oleoyl β-d-galactopyranosylamine (GOA) undergo a morphological transition to fibers consisting of mainly flat sheet-like structures. Moreover, we show that this transformation is reversible in a temperature-dependent manner. We used several optical microscopy and electron microscopy techniques, circular dich

SUBMITTER: Johnson M 

PROVIDER: S-EPMC8849015 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature