Demographics, clinical characteristics, and prognostic factors of amyotrophic lateral sclerosis in Midwest.

ABSTRACT:

Introduction/aims

The Midwest has the highest regional prevalence of self-reported amyotrophic lateral sclerosis (ALS) in the United States, but with limited epidemiological studies. We aimed to explore the characteristics of patients with ALS in the Midwest.

Methods

This was a retrospective cohort study of participants with ALS deceased between January, 2010, and September, 2020, registered with the ALS Association Mid-America Chapter. Demographics and clinical variables included gender, race/ethnicity, military status, site of onset, interventions (gastrostomy, non-invasive ventilation, tracheostomy), and visits to ALS Association-registered clinics. Disease characteristics were compared to the National ALS Registry, and survival analysis was performed followed by sample a

SUBMITTER: Yamakawa M 

PROVIDER: S-EPMC8849587 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature