Temporal trends of multiple sclerosis disease activity: Electronic health records indicators.

ABSTRACT:

Background

Long-term data on multiple sclerosis (MS) inflammatory disease activity are limited. We examined electronic health records (EHR) indicators of disease activity in people with MS.

Methods

We analyzed prospectively collected research registry data and linked EHR data in a clinic-based cohort from 2000 to 2016. We used the trend of the yearly incident relapse rate from the registry data as benchmark. We then calculated the temporal trends of potentially relevant EHR measures, including mean count of the MS diagnostic code, mentions of MS-related concepts, MS-related health utilizations and selected prescriptions.

Results

1,555 MS patients had both registry and EHR data. Between 2000 and 2016, the registry data showed a declining trend in the yearly incident re

SUBMITTER: Liang L 

PROVIDER: S-EPMC8849591 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature