Outcomes of amoebic, fungal, and bacterial keratitis: A retrospective cohort study.

ABSTRACT:

Background

Acanthamoeba keratitis is challenging to treat and thought to result in poor outcomes, but very few comparative studies exist to assess whether ulcers caused by Acanthamoeba are worse than those caused by bacteria or fungus.

Methods

In a retrospective cohort study, all cases of smear- or culture-proven Acanthamoeba keratitis diagnosed from January 2006 to June 2011 at an eye hospital in South India were identified from the microbiology database. Random samples of the same number of cases of bacterial and fungal keratitis, matched by year, were identified from the same database in order to compare outcomes between the three types of organism. The main outcomes were the time until the following events: re-epithelialization, discontinuation of antimicrobials, perfora

SUBMITTER: Moe CA 

PROVIDER: S-EPMC8849599 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature