Association between the Oxidative Balance Score and Telomere Length from the National Health and Nutrition Examination Survey 1999-2002.

ABSTRACT:

Purpose

Leukocyte telomere length (LTL) is an important biomarker of aging. The oxidative balance score (OBS) is used to assess the oxidative stress-related exposures of diet and lifestyle. This study is aimed at exploring if the OBS was associated with LTL.

Methods

3220 adults were included in this study from the National Health and Nutrition Examination Survey (NHANES) 1999-2002. LTL was assayed from leukocyte DNA. Twenty dietary and lifestyle factors were selected to score the OBS. Survey-based multivariable linear regression was conducted to assess the association between the OBS and log-transformed LTL.

Results

The association between the OBS and log-transformed LTL was positive in females but not males. For females, compared with the lowest OBS category as a ref

SUBMITTER: Zhang W 

PROVIDER: S-EPMC8850082 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature