Prechoroidal cleft thickness correlates with disease activity in neovascular age-related macular degeneration.

ABSTRACT:

Purpose

The purpose of this study was to investigate the structural variations of the hyporeflective pocket of fluid (prechoroidal cleft) located between Bruch's membrane and the hyperreflective material within the pigment epithelial detachment (PED) in patients with neovascular age-related macular degeneration (nAMD).

Methods

In this retrospective, observational case series study, patients diagnosed with nAMD and prechoroidal cleft associated with other activity signs of the macular neovascularization (MNV) were included. Structural optical coherence tomography (OCT) scans were evaluated to obtain anatomical measurements of prechoroidal cleft and PED at three different visits (T0, inactive MNV; T1, active MNV; T2, treated inactive MNV). The variations in size of the cleft a

SUBMITTER: Cozzi M 

PROVIDER: S-EPMC8850287 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature