An adaptive planning strategy in carbon ion therapy of pancreatic cancer involving beam angle selection.

ABSTRACT:

Background and purpose

In carbon-ion radiotherapy for pancreatic cancer, altered dose distributions due to changes in the gastrointestinal gas volume and anatomy during irradiation are an unresolved therapeutic issue. We developed and investigated an adaptive strategy involving beam angle selection to improve dose distributions in pancreatic cancer.

Materials and methods

In the adaptive strategy, multiple beams were prepared with angles similar to those of the conventional strategy, and the beam that best reproduces the dose distribution of the treatment plan was used. The dose distributions of the adaptive strategy were compared with those of the conventional strategy for five patients. Patients underwent computed tomography (CT) before every irradiation. The adaptive strat

SUBMITTER: Kawashima M 

PROVIDER: S-EPMC8850338 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature