Frequency of Hepatitis B Virus infection among Patients before Chemotherapy Treatment.

ABSTRACT:

Background

Hepatitis B virus (HBV) is an important public health problem worldwide. Chronic HBV in patients undergoing chemotherapy and immunosuppressive treatment are at risk of HBV reactivation. The consequence of HBV reactivation in immunosuppressed patients may lead to liver failure and death. Therefore, this study was conducted to investigate the frequency of HBV markers in cancer patients before chemotherapy.

Materials and methods

In this study cross-sectional, blood samples were collected from 90 cancer patients before chemotherapy. The patient's sera were tested for the presence of HBsAg and anti-HBc using enzyme-linked immunosorbent assay (ELISA). The HBVDNA was tested for patient's sera using nested polymerase chain reaction (nested-PCR).

Results

Among 90 pa

SUBMITTER: Mahmoudvand S 

PROVIDER: S-EPMC8850890 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature