Association of network connectivity via resting state functional MRI with consciousness, mortality, and outcomes in neonatal acute brain injury.

ABSTRACT:

Background

An accurate and comprehensive test of integrated brain network function is needed for neonates during the acute brain injury period to inform on morbidity. This retrospective cohort study assessed whether integrated brain network function acquired by resting state functional MRI during the acute period in neonates with brain injury, is associated with acute exam, neonatal mortality, and 6-month outcomes.

Methods

Study subjects included 40 consecutive neonates with resting state functional MRI acquired within 31 days after suspected brain insult from March 2018 to July 2019 at Phoenix Children's Hospital. Acute-period exam and test results were assigned ordinal scores based on severity as documented by respective treating specialists. Analyses (Fisher exact, Wilcox

SUBMITTER: Boerwinkle VL 

PROVIDER: S-EPMC8851268 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature