Plasma Levels of Bile Acids Are Related to Cardiometabolic Risk Factors in Young Adults.

ABSTRACT:

Context

Bile acids (BA) are known for their role in intestinal lipid absorption and can also play a role as signaling molecules to control energy metabolism. Prior evidence suggests that alterations in circulating BA levels and in the pool of circulating BA are linked to an increased risk of obesity and a higher incidence of type 2 diabetes in middle-aged adults.

Objective

We aimed to investigate the association between plasma levels of BA with cardiometabolic risk factors in a cohort of well-phenotyped, relatively healthy young adults.

Methods

Body composition, brown adipose tissue, serum classical cardiometabolic risk factors, and a set of 8 plasma BA (including glyco-conjugated forms) in 136 young adults (age 22.1 ± 2.2 years, 67% women) were measured.

Results</

SUBMITTER: Osuna-Prieto FJ 

PROVIDER: S-EPMC8851912 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature