Protocol for individual participant data meta-analysis of interventions for post-traumatic stress.

ABSTRACT:

Introduction

Several evidence-based treatments are effective for post-traumatic stress disorder (PTSD), yet a substantial proportion of patients do not respond or dropout of treatment. We describe the protocol for a systematic review and individual participant data meta-analysis (IPD-MA) aimed at assessing the effectiveness and adverse effects of psychotherapy and pharmacotherapy interventions for treating PTSD. Additionally, we seek to examine moderators and predictors of treatment outcomes.

Method and analysis

This IPD-MA includes randomised controlled trials comparing psychotherapy and pharmacotherapy interventions for PTSD. PubMed, Embase, PsycINFO, PTSDpubs and CENTRAL will be screened up till the 11th of January 2021. The target population is adults with above-threshol

SUBMITTER: Wright SL 

PROVIDER: S-EPMC8852733 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature