The German Gestational Diabetes Study (PREG), a prospective multicentre cohort study: rationale, methodology and design.

ABSTRACT:

Introduction

Even well-treated gestational diabetes mellitus (GDM) might still have impact on long-term health of the mother and her offspring, although this relationship has not yet been conclusively studied. Using in-depth phenotyping of the mother and her offspring, we aim to elucidate the relationship of maternal hyperglycaemia during pregnancy and adequate treatment, and its impact on the long-term health of both mother and child.

Methods

The multicentre PREG study, a prospective cohort study, is designed to metabolically and phenotypically characterise women with a 75-g five-point oral glucose tolerance test (OGTT) during, and repeatedly after pregnancy. Outcome measures are maternal glycaemia during OGTTs, birth outcome and the health and growth development of the off

SUBMITTER: Fritsche L 

PROVIDER: S-EPMC8852757 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature