Metabolic adaptation delays time to reach weight loss goals.

ABSTRACT:

Objective

The aim of this study was to determine whether metabolic adaptation, at the level of resting metabolic rate, was associated with time to reach weight loss goals, after adjusting for confounders.

Methods

A total of 65 premenopausal women with overweight (BMI: 28.6 ± 1.5 kg/m² ; age: 36.4 ± 5.9 years; 36 were White, and 29 were Black) followed an 800-kcal/d diet until BMI ≤25 kg/m² . Body weight and composition were measured at baseline and after weight loss. Dietary adherence was calculated from total energy expenditure, determined by double labeled water, and body composition changes. Metabolic adaptation was defined as a significantly lower measured versus predicted resting metabolic rate (from own regression model). A regression model to pre

SUBMITTER: Martins C 

PROVIDER: S-EPMC8852805 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature