Knowledge-Based Volumetric Modulated Arc Therapy Treatment Planning for Breast Cancer.

ABSTRACT:

Purpose

To create and to validate knowledge-based volumetric modulated arc therapy (VMAT) models for breast cancer treatments without lymph node irradiation.

Materials and methods

One hundred VMAT-based breast plans (manual plans [MP]) were selected to create two knowledge-based VMAT models (breast left and breast right) using RapidPlan™. The plans were generated on Eclipse v15.5 (Varian Medical Systems, Palo Alto, CA) with 6 MV of a Novalis Tx equipped with a high-resolution multileaf collimator. The models were verified based on goodness-of-fit statistics using the coefficients of determination (R ²) and Chi-square (χ²), and the goodness-of-estimation statistics through the mean square error (MSE). Geometrical and dosimetrical constraints were

SUBMITTER: Apaza Blanco OA 

PROVIDER: S-EPMC8853452 | biostudies-literature | 2021 Oct-Dec

REPOSITORIES: biostudies-literature