Reemergence of yellow fever virus in southeastern Brazil, 2017-2018: What sparked the spread?

ABSTRACT:

Background

The 2017-2018 yellow fever virus (YFV) outbreak in southeastern Brazil marked a reemergence of YFV in urban states that had been YFV-free for nearly a century. Unlike earlier urban YFV transmission, this epidemic was driven by forest mosquitoes. The objective of this study was to evaluate environmental drivers of this outbreak.

Methodology/principal findings

Using surveillance data from the Brazilian Ministry of Health on human and non-human primate (NHP) cases of YFV, we traced the spatiotemporal progression of the outbreak. We then assessed the epidemic timing in relation to drought using a monthly Standardized Precipitation Evapotranspiration Index (SPEI) and evaluated demographic risk factors for rural or outdoor exposure amongst YFV cases. Finally, we develop

SUBMITTER: Rosser JI 

PROVIDER: S-EPMC8853510 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature