Lifestyle changes in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis.

ABSTRACT:

Background

Non-alcoholic fatty liver disease is a liver condition that is increasing worldwide and expected to become the number one cause of cirrhosis and hepatocellular carcinoma in the next 5 years. Currently there are no successful or approved pharmacological treatments. Weight loss is the first-line therapy as a 7 to 10% reduction improves steatosis, inflammation, hepatocyte ballooning, and fibrosis. To achieve this, lifestyle interventions including daily exercise and diet must be encouraged. We aimed to assess the effects of diet, exercise, or a combination of both compared to conventional treatment in patients with non-alcoholic fatty liver disease.

Methods and finding

A literature search was performed in CENTRAL, EMBASE, and PubMed. Randomized controlled trials comp

SUBMITTER: Fernandez T 

PROVIDER: S-EPMC8853532 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature