Zinc and selenium supplementation in COVID-19 prevention and treatment: a systematic review of the experimental studies.

ABSTRACT:

Background and aim

The COVID-19 pandemic has severely affected the world's population in the last two years. Along with non-pharmacological public health interventions, major efforts have also been made to identify effective drugs or active substances for COVID-19 prevention and treatment. These include, among many others, the trace elements zinc and selenium, based on laboratory studies and some observational human studies. However, both of these study designs are not adequate to identify and approve treatments in human medicine, and experimental studies in the form of randomized controlled trials are needed to demonstrate the effectiveness and the safety of any interventions.

Methods

We undertook a systematic review in which we searched for published and unpublished clinic

SUBMITTER: Balboni E 

PROVIDER: S-EPMC8853960 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature