The association between prolonged sedentary time and coronary artery calcification in young healthy men in Korea: a cohort study.

ABSTRACT: Coronary artery calcium score (CACS) is a useful method for predicting coronary artery disease in asymptomatic adults. In this study, we investigated the association between prolonged sedentary time and CACS. A cohort study was conducted in 14949 men with negative CACS (CACS = 0) at baseline who were followed up at least once. Sedentary time was categorized into < 7, 7-8, and ≥ 9 h/day. CACS was calculated by cardiac tomography. During 60,112.1 person-years of follow-up, 569 participants developed positive CACS. The multivariable adjusted hazard ratios (95% confidence intervals) for incident positive CACS comparing sedentary times of 7-8 h/day and ≥ 9 h/day to sedentary time of < 7 h/day were 1.25 (0.97-1.62) and 1.28 (1.03-1.59), respectively. This association was more strongly observed i

SUBMITTER: Nam MW 

PROVIDER: S-EPMC8854407 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature