Family History of Breast Cancer and Mammographic Breast Density in Premenopausal Women.

ABSTRACT:

Importance

Family history of breast cancer (FHBC) and mammographic breast density are independent risk factors for breast cancer, but the association of FHBC and mammographic breast density in premenopausal women is not well understood.

Objectives

To investigate the association of FHBC and mammographic breast density in premenopausal women using both quantitative and qualitative measurements.

Design, setting, and participants

This single-center cohort study examined 2 retrospective cohorts: a discovery set of 375 premenopausal women and a validation set of 14 040 premenopausal women. Data from women in the discovery set was collected between December 2015 and October 2016, whereas data from women in the validation set was collected between June 2010 and December 2015.

SUBMITTER: Han Y 

PROVIDER: S-EPMC8855232 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature