Fine particulate matter and polycystic ovarian morphology.

ABSTRACT:

Background

Polycystic ovary morphology (PCOM) is an ultrasonographic finding that can be present in women with ovulatory disorder and oligomenorrhea due to hypothalamic, pituitary, and ovarian dysfunction. While air pollution has emerged as a possible disrupter of hormone homeostasis, limited research has been conducted on the association between air pollution and PCOM.

Methods

We conducted a longitudinal cohort study using electronic medical records data of 5,492 women with normal ovaries at the first ultrasound that underwent a repeated pelvic ultrasound examination during the study period (2004-2016) at Boston Medical Center. Machine learning text algorithms classified PCOM by ultrasound. We used geocoded home address to determine the ambient annual average PM_2.5

SUBMITTER: Fruh V 

PROVIDER: S-EPMC8855564 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature