Transcriptome Responses to Defined Insecticide Selection Pressures in the German Cockroach (Blattella germanica L.).

ABSTRACT: Cockroaches are important global urban pests from aesthetic and health perspectives. Insecticides represent the most cost-effective way to control cockroaches and limit their impacts on human health. However, cockroaches readily develop insecticide resistance, which can quickly limit efficacy of even the newest and most effective insecticide products. The goal of this research was to understand whole-body physiological responses in German cockroaches, at the metatranscriptome level, to defined insecticide selection pressures. We used the insecticide indoxacarb as the selecting insecticide, which is an important bait active ingredient for cockroach control. Six generations of selection with indoxacarb bait produced a strain with substantial (>20×) resistance relative to inbred control lines

SUBMITTER: Scharf ME 

PROVIDER: S-EPMC8856671 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature