High-resolution three‑dimensional contrast‑enhanced magnetic resonance venography in children: comparison of gadofosveset trisodium with ferumoxytol.

ABSTRACT:

Background

Gadofosveset is a gadolinium-based blood pool contrast agent that was approved by the United States Food and Drug Administration in 2008. Its unanticipated withdrawal from production in 2016 created a void in the blood pool agent inventory and highlighted the need for an alternative agent with comparable imaging properties.

Objective

The purpose of our study is to compare the diagnostic image quality, vascular contrast-to-noise ratio (CNR) and temporal signal characteristics of gadofosveset trisodium and ferumoxytol at similar molar doses for high-resolution, three-dimensional (3-D) magnetic resonance (MR) venography in children.

Materials and methods

The medical records and imaging data sets of patients who underwent high-resolution 3-D gadofosveset-enhanc

SUBMITTER: Shahrouki P 

PROVIDER: S-EPMC8857136 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature