Burn Resuscitation Practices in North America: Results of the Acute Burn ResUscitation Multicenter Prospective Trial (ABRUPT).

ABSTRACT:

Objectives

ABRUPT was a prospective, noninterventional, observational study of resuscitation practices at 21 burn centers. The primary goal was to examine burn resuscitation with albumin or crystalloids alone, to design a future prospective randomized trial.

Summary background data

No modern prospective study has determined whether to use colloids or crystalloids for acute burn resuscitation.

Methods

Patients ≥18 years with burns ≥ 20% total body surface area (TBSA) had hourly documentation of resuscitation parameters for 48 hours. Patients received either crystalloids alone or had albumin supplemented to crystalloid based on center protocols.

Results

Of 379 enrollees, two-thirds (253) were resuscitated with albumin and one-third (126) were resuscitated with cr

SUBMITTER: Greenhalgh DG 

PROVIDER: S-EPMC8857312 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature