Pancreatoblastoma in children: Clinical management and literature review.

ABSTRACT:

Purpose

The aim of this study is to analyze the clinical and pathological features of pancreatoblastoma (PB) and to obtain better management for patients with relapsed or metastatic disease.

Methods

Four cases treated in our institution and 59 cases reported previously in the literature from the PubMed biomedical database (2000-2020) were reviewed and analyzed.

Results

Four cases with PB presented with abdominal pain and palpable abdominal masses, with the tumor size ranging from 5.2 to 18 cm in diameter. The invasion of the splenic vein and superior mesenteric artery, duodenum, and lymph nodes were risk factors for PB. Three cases were treated with combination therapy and showed favorable outcomes, while one case was treated with chemotherapy alone due to tumor progr

SUBMITTER: Liu T 

PROVIDER: S-EPMC8857517 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature