Extended characterisation of five archival tick-borne viruses provides insights for virus discovery in Australian ticks.

ABSTRACT:

Background

A subset of Australians who have been bitten by ticks experience a complex of chronic and debilitating symptoms which cannot be attributed to the known pathogenic species of bacteria present in Australia. As a result, there has been a renewed effort to identify and characterise viruses in Australian terrestrial ticks. Recent transcriptome sequencing of Ixodes and Amblyomma ticks has revealed the presence of multiple virus sequences. However, without virus isolates our ability to understand the host range and pathogenesis of newly identified viruses is limited. We have established a successful method for high-throughput virus discovery and isolation in mosquitoes using antibodies to double-stranded RNA. In this study we sought to characterise five archival tick-borne viru

SUBMITTER: O'Brien CA 

PROVIDER: S-EPMC8857802 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature